English VERSION
首页
单位简介
科研进展
科研成果
研究团队
党建园地
人才中心
研究生培养
平台建设
联系我们
人才中心
 
您现在的位置:首页 >> 人才中心 >> 全国农业科研杰出人才

全国农业科研杰出人才   王笑梅

中国农科院二级岗位人才

863领域专家组成员、全国农业科研杰出人才获得者,世界禽病理杂志《Avian pathology》顾问委员会成员。现任中国农业科学院哈尔滨兽医研究所副所长、兽医生物技术国家重点开放实验室常务副主任兼任全国动物疫病防控委员会禽病专家组组长、中国畜牧兽医学会兽医生物技术分会理事长、畜牧兽医学会禽病学分会副理事长、中国免疫学会兽医免疫分会主任委员、国家肉鸡产业技术体系疾病控制功能研究室主任等。先后主持公益性行业专项、十一五973课题、863课题、IBD OIE Twinning项目等国家和省部级科研课题30余项。工作以来,一直从事传染性法氏囊病等禽免疫抑制病的研究,在基础研究和应用研究方面取得一系列成果。成功建立了传染性法氏囊病毒、禽白血病病毒、禽网状内皮组织增生症病毒和鸡传染性贫血病毒反向遗传操作技术平台和酵母表达技术平台。在传染性法氏囊病毒遗传变异、基因功能、强弱毒致病差异机制以及禽白血病病毒致瘤机制等方面取得了重要研究进展。

 

先后在Journal of Virology、Virology、Journal of General Virology等国际重要病毒学学术刊物发表SCI论文60多篇,获得省、市级科技进步奖8项,获发明专利10余项,培养博士研究生14名、硕士研究生37名。

近期发表的主要论文

1. Gao L, Li K, Qi XL, Gao HL, Gao YL, Qin LT, Wang YQ, Shen N, Kong XG Wang XM*. The triplet amino acids located at 145/146/147 of the RNA polymerase of very virulent infectious bursal disease virus contribute to viral virulence. J Gen Virol. 2014, 95(Pt 4): 888-897.

2. Gao Q, Yun BL, Wang Q, Jiang LL, Zhu HB, Gao YN, Qin LT, Wang YQ, Qi XL, Gao HL, Wang XM*, Gao YL*. Development and application of a multiplex PCR method for rapid differential detection of subgroup A, B, and J avian leukosis viruses. J Clin Microbiol. 2014, 52(1): 37-44.

3. Ji XL, Wang Q, Li XF, Qi XL, Wang YQ, Gao HL, Gao YL, Wang XM*. A 19-nucleotide insertion in the leader sequence of avian leukosis virus subgroup J contributes to its replication in vitro but is not related to its pathogenicity in vivo. PLOS One. 2014, 9(1): e84797.

4. Jiang LL, Zeng XW, Hua YP, Gao Q, Fan Z, Chai HL, Wang Q, Qi XL, Wang YQ, Gao HL, Gao YL*, Wang XM*. Genetic diversity and phylogenetic analysis of glycoprotein gp85 of avian leukosis virus subgroup J wild-bird isolates from Northeast China. Arch Virol. 2014, 95(Pt 4): 888-897.

5. Li K, Gao L, Gao HL, Qi XL, Gao YL, Qin LT, Wang YQ, Wang XM*. Recombinant infectious bursal disease virus expressing Newcastle disease virus (NDV) neutralizing epitope confers partial protection against virulent NDV challenge in chickens. Antiviral Res. 2014, 101: 1-11.

6. Qi XL, Chen YM, Ren XG, Zhang LZ, Gao L, Wang N, Qin LT, Wang YQ, Gao YL, Wang XM*. A reassortment vaccine candidate as the improved formulation to induce protection against very virulent infectious bursal disease virus. Vaccine. 2014, 32: 1436-1443.

7. Cui HY, Gao HB, Cui XL, Zhao Y, Shi XM, Li QL, Yan S, Gao M, Wang M, Liu CJ, Wang YF*. A virulent Marek’s Disease Virus type 1 strain 814 vectored vaccine expressing Avian Influenza (AI) Virus H5 haemagglutinin induced better protection than turkey Herpesvirus vectored AI vaccine. PLOS One. 2013, 8: e53340.

8. Gao HL, Li K, Gao L, Qi XL, Gao YL, Qin LT, Wang YQ, Wang XM*. DNA prime-protein boost vaccination enhances protective immunity against infectious bursal disease virus in chickens. Vet Microbiol. 2013, 164(1-2): 9-17.

9. Ji XL, Wang Q, Gao YL, Wang YQ, Qin LT, Qi XL, Gao HL, Wang XM. Development of a new duplex real-time polymerase chain reaction assay for detection of dicer in G. gallus. J Microbiol Biotechnol. 2013, 3(5): 630-636.

10. Jiang LL, Qi XL, Gao YL, Hua YP, Li K, Wang Q, Zhang LZ, Deng XY, Wang Q, Zhang LZ, Chai HL, Chen YM, Yin CH, Gao HL, Qin LT, Wang Y, Qu Y, Chen Q, Fan ZB*, Wang XM*. Molecular characterization and phylogenetic analysis of the reticuloendotheliosis virus isolated from wild birds in Northeast China. Vet Microbiol. 2013, 166(1-2): 68-75.

 

 

 

 
版权所有:中国农业科学院哈尔滨兽医研究所 黑ICP备15009860号
COPYRIGHT © 2015 HVRI.AC.CN ALL RIGHTS RESERVED 技术支持:杉夏文化 访问次数:

黑公网安备 23010302000224号

 
关闭