2017年度代表文章：

1.Shi J, Deng G, Kong H, Gu C, Ma S, Yin X, Zeng X, Cui P, Chen Y, Yang H, Wan X, Wang X, Liu L, Chen P, Jiang Y, Liu J, Guan Y, Suzuki Y, Li M, Qu Z, Guan L, Zang J, Gu W, Han S, Song Y, Hu Y, Wang Z, Gu L, Yang W, Liang L, Bao H, Tian G, Li Y, Qiao C, Jiang L, Li C, Bu Z, Chen H*. 2017. H7N9 virulent mutants detected in chickens in China pose an increased threat to humans. Cell Res doi:10.1038/cr.2017.129.

2.Wang Z, Yang H, Chen Y, Tao S, Liu L, Kong H, Ma S, Meng F, Suzuki Y, Qiao C, Chen H*. 2017. A Single-Amino-Acid Substitution at Position 225 in Hemagglutinin Alters the Transmissibility of Eurasian Avian-Like H1N1 Swine Influenza Virus in Guinea Pigs. J Virol doi:10.1128/JVI.00800-17.

3.Zhao D, Liang L, Wang S, Nakao T, Li Y, Liu L, Guan Y, Fukuyama S, Bu Z, Kawaoka Y, Chen H*. 2017. Glycosylation of the Hemagglutinin Protein of H5N1 Influenza Virus Increases Its Virulence in Mice by Exacerbating the Host Immune Response. J Virol doi:10.1128/JVI.02215-16.

4.Zhu P, Liang L, Shao X, Luo W, Jiang S, Zhao Q, Sun N, Zhao Y, Li J, Wang J, Zhou Y, Zhang J, Wang G, Jiang L, Chen H*, Li C*. 2017. Host cellular protein TRAPPC6ADelta interacts with influenza A virus M2 protein and regulates viral propagation by modulating M2 trafficking. J Virol doi:10.1128/JVI.01757-16.

5.Ge Y, Chai H, Fan Z, Wang X, Yao Q, Ma J, Chen S, Hua Y, Deng G, Chen H*. 2017. New H6 influenza virus reassortment strains isolated from Anser fabalis in Anhui Province, China. Virol J 14:36.

6.Ma Y, Sun J, Gu L, Bao H, Zhao Y, Shi L, Yao W, Tian G, Wang X*, Chen H*. 2017. Annexin A2 (ANXA2) interacts with nonstructural protein 1 and promotes the replication of highly pathogenic H5N1 avian influenza virus. BMC Microbiol 17:191.

7.Qu Z, Ma S, Kong H, Deng G, Shi J, Liu L, Suzuki Y, Chen H*. 2017. Identification of a key amino acid in hemagglutinin that increases human-type receptor binding and transmission of an H6N2 avian influenza virus. Microbes Infect doi:10.1016/j.micinf.2017.09.008.

8.Wang X, Gu L, Shi J, Xu H, Zhang Y, Zeng X, Deng G, LI C*, Chen H*. 2017. Development of a real-time RT-PCR method for the detection of newly emerged highly pathogenic H7N9 influenza viruses. Journal of Integrative Agriculture 16:2055-2061.

9.Wu Y, Yang D, Xu B, Liang W, Sui J, Chen Y, Yang H, Chen H, Wei P, Qiao C*. 2017. Immune efficacy of an adenoviral vector-based swine influenza vaccine against antigenically distinct H1N1 strains in mice. Antiviral Res 147:29-36.

10.Zhang K, Xu WW, Zhang Z, Liu J, Li J, Sun L, Sun W, Jiao P, Sang X, Ren Z, Yu Z, Li Y, Feng N, Wang T, Wang H, Yang S, Zhao Y, Zhang X, Wilker PR, Liu W, Liao M, Chen H, Gao Y, Xia X. 2017. The innate immunity of guinea pigs against highly pathogenic avian influenza virus infection. Oncotarget 8:30422-30437.

 2016年度代表文章：

1.Cui P, Deng G, Shi J, Kong H, Liu L, Guan Y, Suzuki Y, Chen H*. 2016. New influenza A(H7N7) viruses detected in live poultry markets in China. Virology 499:165-169.

2.Feng X, Wang Z, Shi J, Deng G, Kong H, Tao S, Li C, Liu L, Guan Y, Chen H*. 2016. Glycine at Position 622 in PB1 Contributes to the Virulence of H5N1 Avian Influenza Virus in Mice. J Virol 90:1872-1879.

3.Li X, Yang J, Liu B, Jia Y, Guo J, Gao X, Weng S, Yang M, Wang L, Wang LF, Cui J, Chen H, Zhu Q. 2016. Co-circulation of H5N6, H3N2, H3N8, and Emergence of Novel Reassortant H3N6 in a Local Community in Hunan Province in China. Sci Rep 6:25549.

4.Liang L, Deng G, Shi J, Wang S, Zhang Q, Kong H, Gu C, Guan Y, Suzuki Y, Li Y, Jiang Y, Tian G, Liu L, Li C, Chen H*. 2016. Genetics, Receptor Binding, Replication, and Mammalian Transmission of H4 Avian Influenza Viruses Isolated from Live Poultry Markets in China. J Virol 90:1455-1469.

5.Liu L, Zeng X, Chen P, Deng G, Li Y, Shi J, Gu C, Kong H, Suzuki Y, Jiang Y, Tian G, Chen H*. 2016. Characterization of Clade 7.2 H5 Avian Influenza Viruses That Continue To Circulate in Chickens in China. J Virol 90:9797-9805.

6.Sui J, Yang D, Qiao C, Xu H, Xu B, Wu Y, Yang H, Chen Y, Chen H*. 2016. Protective efficacy of an inactivated Eurasian avian-like H1N1 swine influenza vaccine against homologous H1N1 and heterologous H1N1 and H1N2 viruses in mice. Vaccine 34:3757-3763.

7.Sun J, Wang X, Wen X, Bao H, Shi L, Tao Q, Jiang Y, Zeng X, Xu X, Tian G, Zheng S, Chen H*. 2016. Identification of a Highly Conserved Epitope on Avian Influenza Virus Non-Structural Protein 1 Using a Peptide Microarray. PLoS One 11:e0149868.

8.Wang W, Sun X, Li Y, Su J, Ling Z, Zhang T, Wang F, Zhang H, Chen H, Ding J, Sun B. 2016. Human antibody 3E1 targets the HA stem region of H1N1 and H5N6 influenza A viruses. Nat Commun 7:13577.

9.Yang H, Chen Y, Qiao C, He X, Zhou H, Sun Y, Yin H, Meng S, Liu L, Zhang Q, Kong H, Gu C, Li C, Bu Z, Kawaoka Y, Chen H*. 2016. Prevalence, genetics, and transmissibility in ferrets of Eurasian avian-like H1N1 swine influenza viruses. Proc Natl Acad Sci U S A 113:392-397.

10.Zeng X, Chen P, Liu L, Deng G, Li Y, Shi J, Kong H, Feng H, Bai J, Li X, Shi W, Tian G*, Chen H*. 2016. Protective Efficacy of an H5N1 Inactivated Vaccine Against Challenge with Lethal H5N1, H5N2, H5N6, and H5N8 Influenza Viruses in Chickens. Avian Dis 60:253-255.

11. Zeng X, Deng G, Liu L, Li Y, Shi J, Chen P, Feng H, Liu J, Guo X, Mao S, Yang F, Chen Z, Tian G*, Chen H*. 2016. Protective Efficacy of the Inactivated H5N1 Influenza Vaccine Re-6 Against Different Clades of H5N1 Viruses Isolated in China and the Democratic People's Republic of Korea. Avian Dis 60:238-240.

12. Jin H, Wang D, Sun J, Cui Y, Chen, G，Zhang X, Zhang J, Li X, Chai H, Gao Y, Li Y, Hua Y. 2016. Pathogenesis and Phylogenetic Analyses of Two Avian Influenza H7N1 Viruses Isolated from Wild Birds. Front Microbiol 7:1066.

2015年度代表文章：

1.Bao H, Feng X, Ma Y, Shi J, Zhao Y, Gu L, Wang X, Chen H*. 2015. Rapid Detection of Subtype H10N8 Influenza Virus by One-Step Reverse Transcription-Loop-Mediated Isothermal Amplification Methods. J Clin Microbiol 53:3884-3887.

2.Bao H, Ma Y, Shi J, Zeng X, Zhao Y, Wang X, Chen H*. 2015. Evaluation and application of a one-step duplex real-time reverse transcription polymerase chain reaction assay for the rapid detection of influenza A (H7N9) virus from poultry samples. Arch Virol 160:2471-2477.

3.Xue C, Tian G, Chen X, Liu Q, Ma J, Xu S, Li X, Chen H, Cao Y (2015). Incorporation of conserved nucleoprotein into in?uenza virus-like particles could provoke a broad protective immune response in BALB/c mice and chickens. Virus Research, 195, 35-42.

4.Deng G, Shi J, Wang J, Kong H, Cui P, Zhang F, Tan D, Suzuki Y, Liu L, Jiang Y, Guan Y, Chen H*. 2015. Genetics, Receptor Binding, and Virulence in Mice of H10N8 Influenza Viruses Isolated from Ducks and Chickens in Live Poultry Markets in China. J Virol 89:6506-6510.

5.Fan Z, Ci Y, Liu L, Ma Y, Jia Y, Wang D, Guan Y, Tian G, Ma J, Li Y, Chen H*. 2015. Phylogenetic and pathogenic analyses of three H5N1 avian influenza viruses (clade 2.3.2.1) isolated from wild birds in Northeast China. Infect Genet Evol 29:138-145.

6.Feng X, Wang Z, Shi J, Deng G, Kong H, Tao S, Li C, Liu L, Guan Y, Chen H*. 2015. Glycine at Position 622 in PB1 Contributes to the Virulence of H5N1 Avian Influenza Virus in Mice. J Virol 90:1872-1879.

7.He S, Shi J, Qi X, Huang G, Chen H, Lu C. 2015. Lethal infection by a novel reassortant H5N1 avian influenza A virus in a zoo-housed tiger. Microbes Infect 17:54-61.

8.Kong H, Zhang Q, Gu C, Shi J, Deng G, Ma S, Liu J, Chen P, Guan Y, Jiang Y, Chen H*. 2015. A live attenuated vaccine prevents replication and transmission of H7N9 virus in mammals. Sci Rep 5:11233.

9.Li C, Jiao S, Wang G, Gao Y, Liu C, He X, Zhang C, Xiao J, Li W, Zhang G, Wei B, Chen H, Wang H. 2015. The Immune Adaptor ADAP Regulates Reciprocal TGF-beta1-Integrin Crosstalk to Protect from Influenza Virus Infection. PLoS Pathog 11:e1004824.

10.Li X, Fu Y, Yang J, Guo J, He J, Guo J, Weng S, Jia Y, Liu B, Li X, Zhu Q, Chen H*. 2015. Genetic and biological characterization of two novel reassortant H5N6 swine influenza viruses in mice and chickens. Infect Genet Evol 36:462-466.

11.Song J, Xu J, Shi J, Li Y, Chen H*. 2015. Synergistic Effect of S224P and N383D Substitutions in the PA of H5N1 Avian Influenza Virus Contributes to Mammalian Adaptation. Sci Rep 5:10510.

12.Wen X, Sun J, Wang X, Bao H, Zhao Y, Zeng X, Xu X, Ma Y, Gu L, Chen H*. 2015. Identification of a novel linear epitope on the NS1 protein of avian influenza virus. BMC Microbiol 15:168.

13.Wen Z, Wu C, Chen W, Zeng X, Shi J, Ge J, Chen H, Bu Z. 2015. Establishment of MDCK Stable Cell Lines Expressing TMPRSS2 and MSPL and Their Applications in Propagating Influenza Vaccine Viruses in Absence of Exogenous Trypsin. Biotechnol Res Int 2015:402628.

14.Xu X, Bao H, Ma Y, Sun J, Zhao Y, Wang Y, Shi J, Zeng X, Li Y, Wang X, Chen H*. 2015. Simultaneous detection of novel H7N9 and other influenza A viruses in poultry by multiplex real-time RT-PCR. Virol J 12:69.

15.Yamaji R, Yamada S, Le MQ, Li C, Chen H, Qurnianingsih E, Nidom CA, Ito M, Sakai-Tagawa Y, Kawaoka Y. 2015. Identification of PB2 mutations responsible for the efficient replication of H5N1 influenza viruses in human lung epithelial cells. J Virol 89:3947-3956.

16.Yang H, Chen Y, Qiao C, Xu C, Yan M, Xin X, Bu Z, Chen H*. 2015. Two different genotypes of H1N2 swine influenza virus isolated in northern China and their pathogenicity in animals. Vet Microbiol 175:224-231.

17.Yu Z, Cheng K, Sun W, Zhang X, Li Y, Wang T, Wang H, Zhang Q, Xin Y, Xue L, Zhang K, Huang J, Yang S, Qin C, Wilker PR, Yue D, Chen H, Gao Y, Xia X. 2015. A PB1 T296R substitution enhance polymerase activity and confer a virulent phenotype to a 2009 pandemic H1N1 influenza virus in mice. Virology 486:180-186.

18.Yu Z, Gao X, Wang T, Li Y, Li Y, Xu Y, Chu D, Sun H, Wu C, Li S, Wang H, Li Y, Xia Z, Lin W, Qian J, Chen H, Xia X, Gao Y. 2015. Fatal H5N6 Avian Influenza Virus Infection in a Domestic Cat and Wild Birds in China. Sci Rep 5:10704.

19.Zhou Z, Li X, Liu J, Dong L, Chen Q, Liu J, Kong H, Zhang Q, Qi X, Hou D, Zhang L, Zhang G, Liu Y, Zhang Y, Li J, Wang J, Chen X, Wang H, Zhang J, Chen H, Zen K, Zhang CY. 2015. Honeysuckle-encoded atypical microRNA2911 directly targets influenza A viruses. Cell Res 25:39-49.