The Research team on animal influenza prevention and control led by Professor Hualan Chen, recently published an article on H5N1 avian influenza vaccines used in poultry. They summarized the recent advances on the development and application of H5N1 avian influenza vaccines. This review article was published in the latest version of Trends in Biotechnology with Professor Chengjun Li as the first author.

Avian influenza vaccines against H5N1 ‘bird flu’   Chengjun Li, Zhigao Bu, and Hualan Chen

    State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, 427 Maduan Street, Nangang District, Harbin, China 150001

     H5N1 avian influenza viruses (AIVs) have spread widely to more than 60 countries spanning three continents. To control the disease, vaccination of poultry is implemented in many of the affected countries, especially in those where H5N1 viruses have become enzootic in poultry and wild birds. Recently, considerable progress has been made toward the development of novel avian influenza (AI) vaccines, especially recombinant virus vector vaccines and DNA vaccines. Here, we will discuss the recent advances in vaccine development and use against H5N1 AIV in poultry. Understanding the properties of the available, novel vaccines will allow for the establishment of rational vaccination protocols, which in turn will help the effective control and prevention of H5N1 AI.

http://www.sciencedirect.com/science/article/pii/S016777991400002X